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Proteins (AREBPs) stabilise these proteins and may be activated (probably indirectly) by MAPKAPK-2. Although they are similar, they are not exactly the same. Vivo studies: changes in cholesterol levels (increased low-density lipoprotein and decreased high-density lipoprotein), liver damage, nephropathy, cardiovascular pathologies as well as conditions pertaining to hormonal imbalance have been reported in response to AAS high-dose or prolonged administration.

Brand Name(s): Cortef, Hydrocortone, Hydrocortone Acetate. In order to gain optimal results from AAS their use must be combined with a carefully planned and managed diet, exercise program and appropriate rest periods.

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